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The main issue in demonstrating GOF activity is to distinguish between mutantp53’s dominant negative (DN) and GOF activities if the cell system has a WT coun-terpart.
2005) investigationshave found PMC to be well above LIP, with asa consequence considerably higher PEEP if setat PMC. Some young adults who are capableof Piaget’s formal operations will vacillatebetween the conventional and postconven-tional levels Some young adults who are capableof Piaget’s formal operations will vacillatebetween the conventional and postconven-tional levels.